Scientists have Discovered Another way in Which Insulin-Producing Cells Die
Scientists in Italy and Texas now have discovered a new way that these cells die by toxic imbalance of a molecule secreted by other pancreatic cells. The death of insulin producing cells in the pancreas is a major defect in diabetes.
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The Study
"Our study shows that neighboring cells called alpha cells can behave like adversaries for beta cells. This was an unexpected finding," said Franco Folli, M.D., Ph.D., professor of medicine/diabetes at The University of Texas Health Science Center at San Antonio. He is co-lead author on the study with Carla Perego, Ph.D., assistant professor of physiology at the University of Milan. There is no balance to help control blood sugar levels.
The New Discovery
Glutamate toxicity is a new mechanism of beta cell destruction not previously known, to scientists. It has not been suspected that alpha cells could themselves be a cause of beta cell damage. Glutamate poisoning is a new candidate mechanism for beta cell destruction in diabetes.
Conclusion
A new test is being developed to test for the toxins that kill the insulin producing cells. This will help with early treatment.
Source: http://www.sciencedaily.com/releases/2011/02/110225122912.htm
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